Cell-Penetrating · Cell-penetrating peptide (CPP) · TAT-002
HIV-1 TAT Protein Peptide
- Drug class
- Cell-penetrating peptide (CPP)
- Status
- Research use only
- Catalog code
- TAT-002
- Also known as
- TAT-002
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What HIV-1 TAT Protein Peptide is studied for
- Intracellular cargo delivery (peptides, siRNA, proteins)
- Endosomal-escape and trafficking studies
- In vitro screens of CPP variants for uptake efficiency
- Structure–activity work on cationic / amphipathic CPPs
Mechanism of action
HIV-1 TAT Protein Peptide sits within the Cell-Penetrating research class (CPC reference TAT-002). CPPs cross cellular membranes through energy-independent direct translocation and/or endocytic uptake driven by cationic residues (arginine-rich sequences) or amphipathic architecture. They are typically conjugated to a cargo of interest. Investigators typically incorporate HIV-1 TAT Protein Peptide as a reference standard, tool ligand, or substrate in the assay contexts listed above. Fluorescent-conjugate flow cytometry and confocal imaging are the standard uptake readouts.
Frequently asked questions
What is HIV-1 TAT Protein Peptide?
HIV-1 TAT Protein Peptide (CPC catalog code TAT-002) is a synthetic cell-penetrating peptide (cpp) in the cell-penetrating category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is HIV-1 TAT Protein Peptide studied for?
Published and internal research programs use HIV-1 TAT Protein Peptide as a reference standard in cell-penetrating workflows — for example, intracellular cargo delivery (peptides, sirna, proteins) and endosomal-escape and trafficking studies. Human clinical evidence is not established.
Is HIV-1 TAT Protein Peptide FDA-approved for human use?
No. HIV-1 TAT Protein Peptide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is HIV-1 TAT Protein Peptide typically used in the lab?
In a cell-penetrating workflow, HIV-1 TAT Protein Peptide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Fluorescent-conjugate flow cytometry and confocal imaging are the standard uptake readouts.
How should HIV-1 TAT Protein Peptide be stored?
Store lyophilized at −20 °C. Aliquot reconstituted stocks to avoid freeze–thaw damage. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the HIV-1 TAT Protein Peptide product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for TAT-002. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to HIV-1 TAT Protein Peptide?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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