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Peptides shop · Chorionic Gonadotropin-beta (109-119) amide (human) · Reference sheet

Chorionic Gonadotropin-beta (109-119) amide (human)

Reference sheet · Endocrine · CPC catalog code HCG-001

Identity

Name
Chorionic Gonadotropin-beta (109-119) amide (human)
Catalog code
HCG-001
Category
Endocrine

Physicochemical properties

Sequence
H-Thr-Cys-Asp-Asp-Pro-Arg-Phe-Gln-Asp-Ser-Ser-OH (trifluoroacetate salt)
One-letter
TCDDPRFQDSS
Residues
11 amino acids
Molecular formula
C50H75N15O22S computed from sequence
Molecular weight
1270.29 g/mol average mass, free peptide, computed
Net charge (pH 7)
-2 (1 basic / 3 acidic)
Hydrophobic residues
27%
Cysteine present
Yes — disulfide formation and oxidation possible

Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.

Reconstitution reference

Volumes for a 1 mg vial of Chorionic Gonadotropin-beta (109-119) amide (human) at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.

10 mg/mL
0.1 mL diluent per 1 mg
5 mg/mL
0.2 mL diluent per 1 mg
2 mg/mL
0.5 mL diluent per 1 mg
1 mg/mL
1 mL diluent per 1 mg

Handling, storage & reconstitution

Upstream storage
-20 ± 5 °C

General guidance for this class

Reference standards in the Endocrine class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

Chorionic Gonadotropin-beta (109-119) amide (human) sits within the Endocrine research class (CPC reference HCG-001). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate Chorionic Gonadotropin-beta (109-119) amide (human) as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Studied for

  • Receptor-binding and functional selectivity studies
  • Second-messenger (cAMP / IP₁) profiling
  • Hypothalamic–pituitary axis feedback modeling
  • Metabolic and glucose-homeostasis research

Frequently asked

What is Chorionic Gonadotropin-beta (109-119) amide (human)?

Chorionic Gonadotropin-beta (109-119) amide (human) (CPC catalog code HCG-001) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Chorionic Gonadotropin-beta (109-119) amide (human) studied for?

Published and internal research programs use Chorionic Gonadotropin-beta (109-119) amide (human) as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.

Is Chorionic Gonadotropin-beta (109-119) amide (human) FDA-approved for human use?

No. Chorionic Gonadotropin-beta (109-119) amide (human) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Chorionic Gonadotropin-beta (109-119) amide (human) typically used in the lab?

In a endocrine workflow, Chorionic Gonadotropin-beta (109-119) amide (human) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Sources

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Related peptides in Endocrine

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Chorionic Gonadotropin-beta (109-145) (human)
N-Acetyl, [Nle4,DPhe7] alpha-MSH (4-10), amide
[Ac-Cys4,DPhe7,Cys10] alpha-MSH (4-13), amide
Glucagon-Like Peptide I (7-36), amide, human
GLP-1 (7-36), amide, chicken, common turkey
GLP-1/Glucagon-Like Peptide, amide, human
Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide
[DTrp6]-LH-RH Triptoreline, Ethyl Amide
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.