We value your privacy

We use cookies to analyze site usage and improve your experience. You can accept all, reject non-essential, or customize. See our Privacy Policy.

Endocrine · Endocrine research peptide · MSH-002

Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide

Research use · ships internationally
$90.00 / 1mg vial
Buy Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide →Browse all peptides
Bulk order for a lab or clinic? See wholesale pricing →
Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide reference vial
Drug class
Endocrine research peptide
Status
Research use only
Catalog code
MSH-002
Also known as
MSH-002
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide is studied for

  • Receptor-binding and functional selectivity studies
  • Second-messenger (cAMP / IP₁) profiling
  • Hypothalamic–pituitary axis feedback modeling
  • Metabolic and glucose-homeostasis research

Mechanism of action

Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide sits within the Endocrine research class (CPC reference MSH-002). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Frequently asked questions

What is Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide?

Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide (CPC catalog code MSH-002) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide studied for?

Published and internal research programs use Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.

Is Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide FDA-approved for human use?

No. Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide typically used in the lab?

In a endocrine workflow, Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

How should Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide be stored?

Store lyophilized at −20 °C, protected from light. Reconstitute in sterile 0.1% BSA/PBS. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for MSH-002. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for MSH-002 →Add to cart · International research catalogBuy Acetyl-(Nle4,Asp5,D-2-Nal7,Lys10)-cyclo-alpha-MSH (4-10) amide in the kindr Peptides Shop →

Related peptides in Endocrine

Thymosin Alpha-1Immune modulation and T-cell support.
View details
Kisspeptin-10Stimulates the HPG axis to support endogenous testosterone.
View details
Melanotan Iα-MSH analog (afamelanotide) studied for photoprotection and melanogenesis.
View details
KPVAnti-inflammatory tripeptide from α-MSH — studied for gut and skin.
View details
N-Acetyl, [Nle4,DPhe7] alpha-MSH (4-10), amideResearch-grade endocrine · CPC MSHS-004
View details
alpha-MSH, amideResearch-grade endocrine · CPC MSHS-001
View details

Continue across the Kindr entity graph

Related evidence, peptides, and clinical tools on the same topic.

Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.