Signaling · Cell-signaling research peptide · SIGN-011
Pannexin-1 (Panx1), Mimetic Blocking Peptide
- Drug class
- Cell-signaling research peptide
- Status
- Research use only
- Catalog code
- SIGN-011
- Also known as
- SIGN-011
- Reviewed
- 2026-06-01 · Kindr Health Clinical Team
What Pannexin-1 (Panx1), Mimetic Blocking Peptide is studied for
- Protein–protein interaction (PPI) mapping
- SH2, SH3, PDZ, and 14-3-3 binding studies
- Allosteric modulator and PPI-inhibitor discovery
- Signal-pathway dissection in cellular models
Mechanism of action
Pannexin-1 (Panx1), Mimetic Blocking Peptide sits within the Signaling research class (CPC reference SIGN-011). Signaling peptides mimic recognition motifs (phosphotyrosine motifs, PDZ ligands, kinase docking sites) or interfere with protein–protein interactions inside the cell, allowing focused perturbation of a single node in a pathway. Investigators typically incorporate Pannexin-1 (Panx1), Mimetic Blocking Peptide as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR, BLI, AlphaScreen, and pulldown / Western readouts.
Frequently asked questions
What is Pannexin-1 (Panx1), Mimetic Blocking Peptide?
Pannexin-1 (Panx1), Mimetic Blocking Peptide (CPC catalog code SIGN-011) is a synthetic cell-signaling research peptide in the signaling category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
What is Pannexin-1 (Panx1), Mimetic Blocking Peptide studied for?
Published and internal research programs use Pannexin-1 (Panx1), Mimetic Blocking Peptide as a reference standard in signaling workflows — for example, protein–protein interaction (ppi) mapping and sh2, sh3, pdz, and 14-3-3 binding studies. Human clinical evidence is not established.
Is Pannexin-1 (Panx1), Mimetic Blocking Peptide FDA-approved for human use?
No. Pannexin-1 (Panx1), Mimetic Blocking Peptide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
How is Pannexin-1 (Panx1), Mimetic Blocking Peptide typically used in the lab?
In a signaling workflow, Pannexin-1 (Panx1), Mimetic Blocking Peptide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR, BLI, AlphaScreen, and pulldown / Western readouts.
How should Pannexin-1 (Panx1), Mimetic Blocking Peptide be stored?
Store lyophilized at −20 °C. Aliquot in DMSO or aqueous buffer per solubility. Follow your institution's standard operating procedures for handling synthetic peptides.
Where does the Pannexin-1 (Panx1), Mimetic Blocking Peptide product page point to?
This kindr reference page mirrors CPC Scientific's catalog metadata for SIGN-011. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.
What quality specifications apply to Pannexin-1 (Panx1), Mimetic Blocking Peptide?
Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.
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