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Opioid · Opioid-receptor research peptide · OPIO-007

Nociceptin / Orphanin FQ

Research use · ships internationally
$85.00 / 1mg vial
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Nociceptin / Orphanin FQ reference vial
Drug class
Opioid-receptor research peptide
Status
Research use only
Catalog code
OPIO-007
Also known as
OPIO-007
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Nociceptin / Orphanin FQ is studied for

  • Opioid-receptor binding and selectivity profiling
  • β-arrestin recruitment and biased-agonism studies
  • Analgesic mechanism research
  • Tolerance and dependence models

Mechanism of action

Nociceptin / Orphanin FQ sits within the Opioid research class (CPC reference OPIO-007). Opioid peptides bind μ, δ, and κ receptors — Gi/o-coupled GPCRs that inhibit adenylate cyclase, activate GIRK channels, and modulate calcium currents to produce analgesia, tolerance, and reward-circuit effects. Investigators typically incorporate Nociceptin / Orphanin FQ as a reference standard, tool ligand, or substrate in the assay contexts listed above. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.

Frequently asked questions

What is Nociceptin / Orphanin FQ?

Nociceptin / Orphanin FQ (CPC catalog code OPIO-007) is a synthetic opioid-receptor research peptide in the opioid category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Nociceptin / Orphanin FQ studied for?

Published and internal research programs use Nociceptin / Orphanin FQ as a reference standard in opioid workflows — for example, opioid-receptor binding and selectivity profiling and β-arrestin recruitment and biased-agonism studies. Human clinical evidence is not established.

Is Nociceptin / Orphanin FQ FDA-approved for human use?

No. Nociceptin / Orphanin FQ is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Nociceptin / Orphanin FQ typically used in the lab?

In a opioid workflow, Nociceptin / Orphanin FQ is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.

How should Nociceptin / Orphanin FQ be stored?

Store lyophilized at −20 °C. Handle as Schedule research reagents where applicable. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Nociceptin / Orphanin FQ product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for OPIO-007. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Nociceptin / Orphanin FQ?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Nociceptin / Orphanin FQ physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for OPIO-007 →Add to cart · International research catalogBuy Nociceptin / Orphanin FQ in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.