We value your privacy

We use cookies to analyze site usage and improve your experience. You can accept all, reject non-essential, or customize. See our Privacy Policy.

Histone / Epigenetic · Histone / epigenetic reader-writer substrate · HIST-017

K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled

Research use · ships internationally
$90.00 / 1mg vial
Buy K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled →Browse all peptides
Bulk order for a lab or clinic? See wholesale pricing →
K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled reference vial
Drug class
Histone / epigenetic reader-writer substrate
Status
Research use only
Catalog code
HIST-017
Also known as
HIST-017
Reviewed
2026-06-01 · Kindr Health Clinical Team

What K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled is studied for

  • HAT / HDAC / HMT / KDM activity assays
  • Bromodomain and chromodomain binding studies
  • Epigenetic inhibitor screening
  • Chromatin-mark specificity profiling

Mechanism of action

K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled sits within the Histone / Epigenetic research class (CPC reference HIST-017). These peptides carry defined post-translational modifications (methylation, acetylation, phosphorylation) at N-terminal histone tail residues, allowing biochemical characterization of writers (HMTs, HATs), erasers (KDMs, HDACs), and readers (bromodomains, chromodomains). Investigators typically incorporate K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

Frequently asked questions

What is K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled?

K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled (CPC catalog code HIST-017) is a synthetic histone / epigenetic reader-writer substrate in the histone / epigenetic category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled studied for?

Published and internal research programs use K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled as a reference standard in histone / epigenetic workflows — for example, hat / hdac / hmt / kdm activity assays and bromodomain and chromodomain binding studies. Human clinical evidence is not established.

Is K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled FDA-approved for human use?

No. K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled typically used in the lab?

In a histone / epigenetic workflow, K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

How should K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled be stored?

Store lyophilized at −20 °C. Reconstitute in low-salt buffer; avoid repeated freeze–thaw. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for HIST-017. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for HIST-017 →Add to cart · International research catalogBuy K(biotin)-W-Histone H2B (108-125); H2B, N-Terminal biotin-labeled in the kindr Peptides Shop →

Related peptides in Histone / Epigenetic

Histone H2B (21-41), biotin labeledResearch-grade histone / epigenetic · CPC HIST-016
View details
[Lys(Ac)12]-Histone H2B (1-22)-GGK(Biotin)-NH2; H2BK12(Ac), biotin-labeledResearch-grade histone / epigenetic · CPC HIST-014
View details
Histone H3 (21-44)-GK(Biotin), biotin-labeled, amideResearch-grade histone / epigenetic · CPC HIST-050
View details
Histone H3 (21-44)-GK(Biotin), biotin-labeledResearch-grade histone / epigenetic · CPC HIST-049
View details
[Lys(Ac)27]-Histone 3 (21-44)-GK(Biotin); H3K27(Ac), biotin-labeledResearch-grade histone / epigenetic · CPC HIST-051
View details
[Lys(Me1)27]-Histone H3 (15-39)-K(Biotin), H3K27(Me1), biotin-labeledResearch-grade histone / epigenetic · CPC HIST-045
View details

Continue across the Kindr entity graph

Related evidence, peptides, and clinical tools on the same topic.

Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.