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Histone / Epigenetic · Histone / epigenetic reader-writer substrate · HIST-009

[pSer42]-Histone H1 (29-59), Tetrahymena thermophila

Research use · ships internationally
$90.00 / 1mg vial
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[pSer42]-Histone H1 (29-59), Tetrahymena thermophila reference vial
Drug class
Histone / epigenetic reader-writer substrate
Status
Research use only
Catalog code
HIST-009
Also known as
HIST-009
Reviewed
2026-06-01 · Kindr Health Clinical Team

What [pSer42]-Histone H1 (29-59), Tetrahymena thermophila is studied for

  • HAT / HDAC / HMT / KDM activity assays
  • Bromodomain and chromodomain binding studies
  • Epigenetic inhibitor screening
  • Chromatin-mark specificity profiling

Mechanism of action

[pSer42]-Histone H1 (29-59), Tetrahymena thermophila sits within the Histone / Epigenetic research class (CPC reference HIST-009). These peptides carry defined post-translational modifications (methylation, acetylation, phosphorylation) at N-terminal histone tail residues, allowing biochemical characterization of writers (HMTs, HATs), erasers (KDMs, HDACs), and readers (bromodomains, chromodomains). Investigators typically incorporate [pSer42]-Histone H1 (29-59), Tetrahymena thermophila as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

Frequently asked questions

What is [pSer42]-Histone H1 (29-59), Tetrahymena thermophila?

[pSer42]-Histone H1 (29-59), Tetrahymena thermophila (CPC catalog code HIST-009) is a synthetic histone / epigenetic reader-writer substrate in the histone / epigenetic category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is [pSer42]-Histone H1 (29-59), Tetrahymena thermophila studied for?

Published and internal research programs use [pSer42]-Histone H1 (29-59), Tetrahymena thermophila as a reference standard in histone / epigenetic workflows — for example, hat / hdac / hmt / kdm activity assays and bromodomain and chromodomain binding studies. Human clinical evidence is not established.

Is [pSer42]-Histone H1 (29-59), Tetrahymena thermophila FDA-approved for human use?

No. [pSer42]-Histone H1 (29-59), Tetrahymena thermophila is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is [pSer42]-Histone H1 (29-59), Tetrahymena thermophila typically used in the lab?

In a histone / epigenetic workflow, [pSer42]-Histone H1 (29-59), Tetrahymena thermophila is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR / BLI binding, AlphaScreen, TR-FRET, and MS-based activity assays.

How should [pSer42]-Histone H1 (29-59), Tetrahymena thermophila be stored?

Store lyophilized at −20 °C. Reconstitute in low-salt buffer; avoid repeated freeze–thaw. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the [pSer42]-Histone H1 (29-59), Tetrahymena thermophila product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for HIST-009. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to [pSer42]-Histone H1 (29-59), Tetrahymena thermophila?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the [pSer42]-Histone H1 (29-59), Tetrahymena thermophila physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for HIST-009 →Add to cart · International research catalogBuy [pSer42]-Histone H1 (29-59), Tetrahymena thermophila in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.