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GI / Gut · Gastrointestinal / gut-hormone peptide · EXED-001

[Des His1, Glu8] Exendin-4

Research use · ships internationally
$85.00 / 1mg vial
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[Des His1, Glu8] Exendin-4 reference vial
Drug class
Gastrointestinal / gut-hormone peptide
Status
Research use only
Catalog code
EXED-001
Also known as
EXED-001
Reviewed
2026-06-01 · Kindr Health Clinical Team

What [Des His1, Glu8] Exendin-4 is studied for

  • Incretin (GLP-1 / GIP) receptor signaling
  • Appetite and satiety-circuit research
  • Gastric motility and emptying assays
  • Gut–brain axis and vagal signaling models

Mechanism of action

[Des His1, Glu8] Exendin-4 sits within the GI / Gut research class (CPC reference EXED-001). Gut peptides engage GPCRs on enteroendocrine cells, vagal afferents, and central nuclei, modulating motility, secretion, satiety, and glucose-dependent insulin release. Investigators typically incorporate [Des His1, Glu8] Exendin-4 as a reference standard, tool ligand, or substrate in the assay contexts listed above. cAMP HTRF, in vitro islet insulin secretion, and food-intake models in rodents.

Frequently asked questions

What is [Des His1, Glu8] Exendin-4?

[Des His1, Glu8] Exendin-4 (CPC catalog code EXED-001) is a synthetic gastrointestinal / gut-hormone peptide in the gi / gut category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is [Des His1, Glu8] Exendin-4 studied for?

Published and internal research programs use [Des His1, Glu8] Exendin-4 as a reference standard in gi / gut workflows — for example, incretin (glp-1 / gip) receptor signaling and appetite and satiety-circuit research. Human clinical evidence is not established.

Is [Des His1, Glu8] Exendin-4 FDA-approved for human use?

No. [Des His1, Glu8] Exendin-4 is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is [Des His1, Glu8] Exendin-4 typically used in the lab?

In a gi / gut workflow, [Des His1, Glu8] Exendin-4 is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. cAMP HTRF, in vitro islet insulin secretion, and food-intake models in rodents.

How should [Des His1, Glu8] Exendin-4 be stored?

Store lyophilized at −20 °C. Reconstitute in acidified water (0.1% acetic acid) for stability. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the [Des His1, Glu8] Exendin-4 product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for EXED-001. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to [Des His1, Glu8] Exendin-4?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the [Des His1, Glu8] Exendin-4 physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for EXED-001 →Add to cart · International research catalogBuy [Des His1, Glu8] Exendin-4 in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.