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Opioid · Opioid-receptor research peptide · ENKP-006

Met-Enkephalin

Research use · ships internationally
$85.00 / 1mg vial
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Met-Enkephalin reference vial
Drug class
Opioid-receptor research peptide
Status
Research use only
Catalog code
ENKP-006
Also known as
ENKP-006
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Met-Enkephalin is studied for

  • Opioid-receptor binding and selectivity profiling
  • β-arrestin recruitment and biased-agonism studies
  • Analgesic mechanism research
  • Tolerance and dependence models

Mechanism of action

Met-Enkephalin sits within the Opioid research class (CPC reference ENKP-006). Opioid peptides bind μ, δ, and κ receptors — Gi/o-coupled GPCRs that inhibit adenylate cyclase, activate GIRK channels, and modulate calcium currents to produce analgesia, tolerance, and reward-circuit effects. Investigators typically incorporate Met-Enkephalin as a reference standard, tool ligand, or substrate in the assay contexts listed above. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.

Frequently asked questions

What is Met-Enkephalin?

Met-Enkephalin (CPC catalog code ENKP-006) is a synthetic opioid-receptor research peptide in the opioid category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Met-Enkephalin studied for?

Published and internal research programs use Met-Enkephalin as a reference standard in opioid workflows — for example, opioid-receptor binding and selectivity profiling and β-arrestin recruitment and biased-agonism studies. Human clinical evidence is not established.

Is Met-Enkephalin FDA-approved for human use?

No. Met-Enkephalin is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Met-Enkephalin typically used in the lab?

In a opioid workflow, Met-Enkephalin is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. GTPγS binding, cAMP HTRF, and β-arrestin PathHunter assays.

How should Met-Enkephalin be stored?

Store lyophilized at −20 °C. Handle as Schedule research reagents where applicable. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Met-Enkephalin product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for ENKP-006. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Met-Enkephalin?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Met-Enkephalin physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for ENKP-006 →Add to cart · International research catalogBuy Met-Enkephalin in the kindr Peptides Shop →

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[DPhe2,5,(pCl)Phe4] EnkephalinResearch-grade opioid · CPC ENKP-005
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[Des-Tyr1,DPen2,Pen5] EnkephalinResearch-grade opioid · CPC ENKP-004
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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.