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Cardiovascular · Cardiovascular research peptide · ENDT-005

Endothelin-3, human

Research use · ships internationally
$90.00 / 1mg vial
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Endothelin-3, human reference vial
Drug class
Cardiovascular research peptide
Status
Research use only
Catalog code
ENDT-005
Also known as
ENDT-005
Reviewed
2026-06-01 · Kindr Health Clinical Team

What Endothelin-3, human is studied for

  • Vascular reactivity in aortic ring and mesenteric bed preparations
  • Renin–angiotensin–aldosterone system (RAAS) mechanistic studies
  • Natriuretic and diuretic pathway characterization
  • Cardiac remodeling and hypertrophy models

Mechanism of action

Endothelin-3, human sits within the Cardiovascular research class (CPC reference ENDT-005). Cardiovascular peptides act on GPCRs and receptor systems in vascular smooth muscle, endothelium, and cardiac myocytes — modulating vasoconstriction, natriuresis, RAAS signaling, or ionotropic responses. Effects are typically measured in isolated vessel, Langendorff heart, or receptor-transfected cell assays.</ Investigators typically incorporate Endothelin-3, human as a reference standard, tool ligand, or substrate in the assay contexts listed above. Radioligand-binding, IP-1 / cAMP HTRF, and organ-bath tension recordings are the standard readouts.

Frequently asked questions

What is Endothelin-3, human?

Endothelin-3, human (CPC catalog code ENDT-005) is a synthetic cardiovascular research peptide in the cardiovascular category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Endothelin-3, human studied for?

Published and internal research programs use Endothelin-3, human as a reference standard in cardiovascular workflows — for example, vascular reactivity in aortic ring and mesenteric bed preparations and renin–angiotensin–aldosterone system (raas) mechanistic studies. Human clinical evidence is not established.

Is Endothelin-3, human FDA-approved for human use?

No. Endothelin-3, human is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Endothelin-3, human typically used in the lab?

In a cardiovascular workflow, Endothelin-3, human is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Radioligand-binding, IP-1 / cAMP HTRF, and organ-bath tension recordings are the standard readouts.

How should Endothelin-3, human be stored?

Stable lyophilized at −20 °C for ≥24 months. Reconstitute in normal saline or PBS. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the Endothelin-3, human product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for ENDT-005. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to Endothelin-3, human?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the Endothelin-3, human physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for ENDT-005 →Add to cart · International research catalogBuy Endothelin-3, human in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.