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Endocrine · Endocrine research peptide · CRFS-005

alpha-Helical Corticotropin Releasing Factor (12-41)

Research use · ships internationally
$90.00 / 1mg vial
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alpha-Helical Corticotropin Releasing Factor (12-41) reference vial
Drug class
Endocrine research peptide
Status
Research use only
Catalog code
CRFS-005
Also known as
CRFS-005
Reviewed
2026-06-01 · Kindr Health Clinical Team

What alpha-Helical Corticotropin Releasing Factor (12-41) is studied for

  • Receptor-binding and functional selectivity studies
  • Second-messenger (cAMP / IP₁) profiling
  • Hypothalamic–pituitary axis feedback modeling
  • Metabolic and glucose-homeostasis research

Mechanism of action

alpha-Helical Corticotropin Releasing Factor (12-41) sits within the Endocrine research class (CPC reference CRFS-005). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate alpha-Helical Corticotropin Releasing Factor (12-41) as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Frequently asked questions

What is alpha-Helical Corticotropin Releasing Factor (12-41)?

alpha-Helical Corticotropin Releasing Factor (12-41) (CPC catalog code CRFS-005) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is alpha-Helical Corticotropin Releasing Factor (12-41) studied for?

Published and internal research programs use alpha-Helical Corticotropin Releasing Factor (12-41) as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.

Is alpha-Helical Corticotropin Releasing Factor (12-41) FDA-approved for human use?

No. alpha-Helical Corticotropin Releasing Factor (12-41) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is alpha-Helical Corticotropin Releasing Factor (12-41) typically used in the lab?

In a endocrine workflow, alpha-Helical Corticotropin Releasing Factor (12-41) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

How should alpha-Helical Corticotropin Releasing Factor (12-41) be stored?

Store lyophilized at −20 °C, protected from light. Reconstitute in sterile 0.1% BSA/PBS. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the alpha-Helical Corticotropin Releasing Factor (12-41) product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for CRFS-005. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to alpha-Helical Corticotropin Releasing Factor (12-41)?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the alpha-Helical Corticotropin Releasing Factor (12-41) physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for CRFS-005 →Add to cart · International research catalogBuy alpha-Helical Corticotropin Releasing Factor (12-41) in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.