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Bone / Cartilage · Bone / cartilage biology peptide · COMA-002

C3a (70-77)

Research use · ships internationally
$95.00 / 1mg vial
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C3a (70-77) reference vial
Drug class
Bone / cartilage biology peptide
Status
Research use only
Catalog code
COMA-002
Also known as
COMA-002
Reviewed
2026-06-01 · Kindr Health Clinical Team

What C3a (70-77) is studied for

  • Osteoblast / osteoclast differentiation assays
  • Chondrocyte and cartilage-explant remodeling studies
  • Bone-resorption and mineralization models
  • Biomaterial functionalization for orthopaedic scaffolds

Mechanism of action

C3a (70-77) sits within the Bone / Cartilage research class (CPC reference COMA-002). These peptides interact with bone- and cartilage-relevant receptors and matrix proteins — including RANK/RANKL, PTH1R, integrins, and collagen-binding motifs — modulating osteoblast, osteoclast, and chondrocyte activity in cellular and organ-culture models. Investigators typically incorporate C3a (70-77) as a reference standard, tool ligand, or substrate in the assay contexts listed above. Commonly paired with ALP, TRAP, or Alizarin Red staining in cell-based readouts.

Frequently asked questions

What is C3a (70-77)?

C3a (70-77) (CPC catalog code COMA-002) is a synthetic bone / cartilage biology peptide in the bone / cartilage category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is C3a (70-77) studied for?

Published and internal research programs use C3a (70-77) as a reference standard in bone / cartilage workflows — for example, osteoblast / osteoclast differentiation assays and chondrocyte and cartilage-explant remodeling studies. Human clinical evidence is not established.

Is C3a (70-77) FDA-approved for human use?

No. C3a (70-77) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is C3a (70-77) typically used in the lab?

In a bone / cartilage workflow, C3a (70-77) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Commonly paired with ALP, TRAP, or Alizarin Red staining in cell-based readouts.

How should C3a (70-77) be stored?

Store lyophilized at −20 °C. Reconstitute in sterile buffer immediately before use. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the C3a (70-77) product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for COMA-002. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to C3a (70-77)?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the C3a (70-77) physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for COMA-002 →Add to cart · International research catalogBuy C3a (70-77) in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.