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Neurodegenerative · Neurodegenerative-disease research peptide · AMYD-122

MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide

Research use · ships internationally
$110.00 / 1mg vial
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MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide reference vial
Drug class
Neurodegenerative-disease research peptide
Status
Research use only
Catalog code
AMYD-122
Also known as
AMYD-122
Reviewed
2026-06-01 · Kindr Health Clinical Team

What MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide is studied for

  • Aggregation kinetics (ThT, ANS fluorescence) studies
  • Oligomer- and fibril-mediated toxicity assays
  • Seeding and prion-like propagation models
  • Aggregation-inhibitor and antibody screening

Mechanism of action

MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide sits within the Neurodegenerative research class (CPC reference AMYD-122). These peptides (amyloid-β, α-synuclein, tau, prion fragments) form ordered β-sheet aggregates and oligomeric species that are used to interrogate seeding, propagation, and cellular toxicity mechanisms of neurodegeneration. Investigators typically incorporate MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide as a reference standard, tool ligand, or substrate in the assay contexts listed above. ThT fluorescence, AFM / TEM morphology, and neuronal-toxicity readouts (LDH, MTT).

Frequently asked questions

What is MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide?

MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide (CPC catalog code AMYD-122) is a synthetic neurodegenerative-disease research peptide in the neurodegenerative category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide studied for?

Published and internal research programs use MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide as a reference standard in neurodegenerative workflows — for example, aggregation kinetics (tht, ans fluorescence) studies and oligomer- and fibril-mediated toxicity assays. Human clinical evidence is not established.

Is MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide FDA-approved for human use?

No. MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide typically used in the lab?

In a neurodegenerative workflow, MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. ThT fluorescence, AFM / TEM morphology, and neuronal-toxicity readouts (LDH, MTT).

How should MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide be stored?

Store lyophilized at −20 °C. Freshly monomerize using HFIP treatment before aggregation experiments. Follow your institution's standard operating procedures for handling synthetic peptides.

Where does the MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide product page point to?

This kindr reference page mirrors CPC Scientific's catalog metadata for AMYD-122. The upstream reference sheet — including sequence, purity, MW, and application notes where published — is linked from the buy panel. All orders placed on kindr Peptides ship internationally under research-use terms only.

What quality specifications apply to MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide?

Research-grade peptides in the CPC catalog are synthesized by solid-phase peptide synthesis (SPPS), purified by preparative RP-HPLC, and characterized by analytical HPLC and mass spectrometry. Typical purity is ≥95%; certificate of analysis is available on request.

Internal reference sheetOpen the MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide physicochemical & handling reference →Upstream reference sheetView CPC Scientific catalog page for AMYD-122 →Add to cart · International research catalogBuy MCA-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-674)-Dap(DNP) Amide in the kindr Peptides Shop →

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Research & medical disclosure. This page is educational reference content reviewed by a licensed physician. It is not medical advice and does not establish a clinician–patient relationship. Peptides offered on the kindr Peptides Shop are sold for in vitro laboratory research purposes only and ship worldwide, including the United States. For U.S. clinical care, use the kindr Longevity intake.