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Peptides shop · Cys-Kemptide · Reference sheet

Cys-Kemptide

Reference sheet · Kinase Substrates · CPC catalog code PKCP-013

Identity

Name
Cys-Kemptide
Catalog code
PKCP-013
Category
Kinase Substrates

Physicochemical properties

Sequence
H-Cys-Leu-Arg-Arg-Ala-Ser-Leu-Gly-OH (trifluoroacetate salt)
One-letter
CLRRASLG
Residues
8 amino acids
Molecular formula
C35H66N14O10S computed from sequence
Molecular weight
875.06 g/mol average mass, free peptide, computed
Net charge (pH 7)
+2 (2 basic / 0 acidic)
Hydrophobic residues
50%
Cysteine present
Yes — disulfide formation and oxidation possible

Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.

Reconstitution reference

Volumes for a 1 mg vial of Cys-Kemptide at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.

10 mg/mL
0.1 mL diluent per 1 mg
5 mg/mL
0.2 mL diluent per 1 mg
2 mg/mL
0.5 mL diluent per 1 mg
1 mg/mL
1 mL diluent per 1 mg

Handling, storage & reconstitution

Upstream storage
-20 ± 5 °C

General guidance for this class

Reference standards in the Kinase Substrates class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

Cys-Kemptide sits within the Kinase Substrates research class (CPC reference PKCP-013). These peptides carry consensus phosphorylation motifs recognized by specific kinase families (PKA, PKC, CDK, MAPK, tyrosine kinases). Phosphorylation is detected via radiolabel incorporation, ADP quantitation, or antibody-based readouts. Investigators typically incorporate Cys-Kemptide as a reference standard, tool ligand, or substrate in the assay contexts listed above. ADP-Glo, HTRF KinEASE, and radiometric filter-binding assays.

Studied for

  • Kinase activity and kinetic characterization
  • High-throughput inhibitor screening
  • Selectivity profiling across kinase panels
  • Substrate-motif specificity mapping

Frequently asked

What is Cys-Kemptide?

Cys-Kemptide (CPC catalog code PKCP-013) is a synthetic kinase / phosphatase substrate in the kinase substrates category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Cys-Kemptide studied for?

Published and internal research programs use Cys-Kemptide as a reference standard in kinase substrates workflows — for example, kinase activity and kinetic characterization and high-throughput inhibitor screening. Human clinical evidence is not established.

Is Cys-Kemptide FDA-approved for human use?

No. Cys-Kemptide is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Cys-Kemptide typically used in the lab?

In a kinase substrates workflow, Cys-Kemptide is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. ADP-Glo, HTRF KinEASE, and radiometric filter-binding assays.

Sources

View full product page →Back to catalog

Related peptides in Kinase Substrates

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.