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Peptides shop · C-Type Natriuretic Peptide (32-53) (human, porcine, rat) · Reference sheet

C-Type Natriuretic Peptide (32-53) (human, porcine, rat)

Reference sheet · Cardiovascular · CPC catalog code NATR-020

Identity

Name
C-Type Natriuretic Peptide (32-53) (human, porcine, rat)
Catalog code
NATR-020
Category
Cardiovascular

Physicochemical properties

Sequence
H-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-OH
One-letter
GLSKGCFGLKLDRIGSMSGLGC
Residues
22 amino acids
Molecular formula
C93H159N27O28S3 computed from sequence
Molecular weight
2199.64 g/mol average mass, free peptide, computed
Net charge (pH 7)
+2 (3 basic / 1 acidic)
Hydrophobic residues
41%
Cysteine present
Yes — disulfide formation and oxidation possible

Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.

Reconstitution reference

Volumes for a 1 mg vial of C-Type Natriuretic Peptide (32-53) (human, porcine, rat) at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.

10 mg/mL
0.1 mL diluent per 1 mg
5 mg/mL
0.2 mL diluent per 1 mg
2 mg/mL
0.5 mL diluent per 1 mg
1 mg/mL
1 mL diluent per 1 mg

Handling, storage & reconstitution

Upstream storage
-20 ± 5 °C

General guidance for this class

Reference standards in the Cardiovascular class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

C-Type Natriuretic Peptide (32-53) (human, porcine, rat) sits within the Cardiovascular research class (CPC reference NATR-020). Cardiovascular peptides act on GPCRs and receptor systems in vascular smooth muscle, endothelium, and cardiac myocytes — modulating vasoconstriction, natriuresis, RAAS signaling, or ionotropic responses. Effects are typically measured in isolated vessel, Langendorff heart, or receptor-transfected cell assays.</ Investigators typically incorporate C-Type Natriuretic Peptide (32-53) (human, porcine, rat) as a reference standard, tool ligand, or substrate in the assay contexts listed above. Radioligand-binding, IP-1 / cAMP HTRF, and organ-bath tension recordings are the standard readouts.

Studied for

  • Vascular reactivity in aortic ring and mesenteric bed preparations
  • Renin–angiotensin–aldosterone system (RAAS) mechanistic studies
  • Natriuretic and diuretic pathway characterization
  • Cardiac remodeling and hypertrophy models

Frequently asked

What is C-Type Natriuretic Peptide (32-53) (human, porcine, rat)?

C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CPC catalog code NATR-020) is a synthetic cardiovascular research peptide in the cardiovascular category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is C-Type Natriuretic Peptide (32-53) (human, porcine, rat) studied for?

Published and internal research programs use C-Type Natriuretic Peptide (32-53) (human, porcine, rat) as a reference standard in cardiovascular workflows — for example, vascular reactivity in aortic ring and mesenteric bed preparations and renin–angiotensin–aldosterone system (raas) mechanistic studies. Human clinical evidence is not established.

Is C-Type Natriuretic Peptide (32-53) (human, porcine, rat) FDA-approved for human use?

No. C-Type Natriuretic Peptide (32-53) (human, porcine, rat) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is C-Type Natriuretic Peptide (32-53) (human, porcine, rat) typically used in the lab?

In a cardiovascular workflow, C-Type Natriuretic Peptide (32-53) (human, porcine, rat) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Radioligand-binding, IP-1 / cAMP HTRF, and organ-bath tension recordings are the standard readouts.

Sources

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Related peptides in Cardiovascular

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

(Tyr0)-C-Type Natriuretic Peptide (32-53) (human, porcine)
BNP (1-32), porcine
BNP (7-32), porcine
BNP (1-32), rat
Atrial Natriuretic Peptide (3-28), human
Atrial Natriuretic Peptide (1-28), rat
[Tyr0] BNP (1-32), human
TAMRA-BNP (1-32), human
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.