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Reference sheet · Protease Substrates · CPC catalog code MMPS-014
This sequence carries terminal or reporter modifications (DNP), so no molecular formula or weight is published here — the modified mass must come from the lot certificate of analysis. Residue composition and charge describe the peptide backbone only. Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.
Volumes for a 1 mg vial of MMP-8 Substrate, Fluorogenic (Neutrophil Collagenase Substrate) at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.
Reference standards in the Protease Substrates class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.
MMP-8 Substrate, Fluorogenic (Neutrophil Collagenase Substrate) sits within the Protease Substrates research class (CPC reference MMPS-014). The peptide encodes a specific protease-recognition motif flanked by a reporter (pNA, AMC, MCA / Dnp FRET pair). Enzymatic cleavage releases the reporter, producing signal directly proportional to catalytic activity. Investigators typically incorporate MMP-8 Substrate, Fluorogenic (Neutrophil Collagenase Substrate) as a reference standard, tool ligand, or substrate in the assay contexts listed above. Read on kinetic plate readers at the reporter-appropriate wavelength.
MMP-8 Substrate, Fluorogenic (Neutrophil Collagenase Substrate) (CPC catalog code MMPS-014) is a synthetic protease substrate (research reagent) in the protease substrates category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
Published and internal research programs use MMP-8 Substrate, Fluorogenic (Neutrophil Collagenase Substrate) as a reference standard in protease substrates workflows — for example, kinetic (kcat / km) protease characterization and inhibitor screening and ic₅₀ determination. Human clinical evidence is not established.
No. MMP-8 Substrate, Fluorogenic (Neutrophil Collagenase Substrate) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
In a protease substrates workflow, MMP-8 Substrate, Fluorogenic (Neutrophil Collagenase Substrate) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Read on kinetic plate readers at the reporter-appropriate wavelength.
Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.