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Peptides shop · IRBP, Interphotoreceptor Retinoid Binding Protein Fragment · Reference sheet

IRBP, Interphotoreceptor Retinoid Binding Protein Fragment

Reference sheet · Signaling · CPC catalog code IRBP-002

Identity

Name
IRBP, Interphotoreceptor Retinoid Binding Protein Fragment
Catalog code
IRBP-002
Category
Signaling

Physicochemical properties

Sequence
H-Ser-Gly-Ile-Pro-Tyr-Ile-Ile-Ser-Tyr-Leu-His-Pro-Gly-Asn-Thr-Ile-Leu-His-Val-Asp-OH (trifluoroacetate salt)
One-letter
SGIPYIISYLHPGNTILHVD
Residues
20 amino acids
Molecular formula
C103H157N25O29 computed from sequence
Molecular weight
2209.54 g/mol average mass, free peptide, computed
Net charge (pH 7)
-0.8 (2 basic / 1 acidic)
Hydrophobic residues
55%
Cysteine present
No

Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.

Reconstitution reference

Volumes for a 1 mg vial of IRBP, Interphotoreceptor Retinoid Binding Protein Fragment at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.

10 mg/mL
0.1 mL diluent per 1 mg
5 mg/mL
0.2 mL diluent per 1 mg
2 mg/mL
0.5 mL diluent per 1 mg
1 mg/mL
1 mL diluent per 1 mg

Handling, storage & reconstitution

Upstream storage
-20 ± 5 °C

General guidance for this class

Reference standards in the Signaling class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

IRBP, Interphotoreceptor Retinoid Binding Protein Fragment sits within the Signaling research class (CPC reference IRBP-002). Signaling peptides mimic recognition motifs (phosphotyrosine motifs, PDZ ligands, kinase docking sites) or interfere with protein–protein interactions inside the cell, allowing focused perturbation of a single node in a pathway. Investigators typically incorporate IRBP, Interphotoreceptor Retinoid Binding Protein Fragment as a reference standard, tool ligand, or substrate in the assay contexts listed above. SPR, BLI, AlphaScreen, and pulldown / Western readouts.

Studied for

  • Protein–protein interaction (PPI) mapping
  • SH2, SH3, PDZ, and 14-3-3 binding studies
  • Allosteric modulator and PPI-inhibitor discovery
  • Signal-pathway dissection in cellular models

Frequently asked

What is IRBP, Interphotoreceptor Retinoid Binding Protein Fragment?

IRBP, Interphotoreceptor Retinoid Binding Protein Fragment (CPC catalog code IRBP-002) is a synthetic cell-signaling research peptide in the signaling category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is IRBP, Interphotoreceptor Retinoid Binding Protein Fragment studied for?

Published and internal research programs use IRBP, Interphotoreceptor Retinoid Binding Protein Fragment as a reference standard in signaling workflows — for example, protein–protein interaction (ppi) mapping and sh2, sh3, pdz, and 14-3-3 binding studies. Human clinical evidence is not established.

Is IRBP, Interphotoreceptor Retinoid Binding Protein Fragment FDA-approved for human use?

No. IRBP, Interphotoreceptor Retinoid Binding Protein Fragment is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is IRBP, Interphotoreceptor Retinoid Binding Protein Fragment typically used in the lab?

In a signaling workflow, IRBP, Interphotoreceptor Retinoid Binding Protein Fragment is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. SPR, BLI, AlphaScreen, and pulldown / Western readouts.

Sources

View full product page →Back to catalog

Related peptides in Signaling

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

IRBP (1-20), human
Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain
eNOS (494-513), Calmodulin Binding Domain
SmMLCKp, Smooth-Muscle Myosin Light-Chain Kinase (796-815), Calmodulin Binding
PDE(p), Calmodulin Binding Domain
Tau-Protein (1-16)
WRW4, Formyl Peptide Receptor-Like 1 (FPRL1) Antagonist
JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.