We value your privacy

We use cookies to analyze site usage and improve your experience. You can accept all, reject non-essential, or customize. See our Privacy Policy.

Peptides shop · IGF-I Analog · Reference sheet

IGF-I Analog

Reference sheet · Growth Factors · CPC catalog code ILGF-002

Identity

Name
IGF-I Analog
Catalog code
ILGF-002
Category
Growth Factors

Physicochemical properties

Sequence
H-Cys-Tyr-Ala-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Cys-OH (trifluoroacetate salt) (Disulfide bond)
One-letter
CYAAPLKPAKSC
Residues
12 amino acids
Molecular formula
C55H90N14O15S2 computed from sequence
Molecular weight
1251.53 g/mol average mass, free peptide, computed
Net charge (pH 7)
+2 (2 basic / 0 acidic)
Hydrophobic residues
75%
Cysteine present
Yes — disulfide formation and oxidation possible

Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.

Reconstitution reference

Volumes for a 1 mg vial of IGF-I Analog at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.

10 mg/mL
0.1 mL diluent per 1 mg
5 mg/mL
0.2 mL diluent per 1 mg
2 mg/mL
0.5 mL diluent per 1 mg
1 mg/mL
1 mL diluent per 1 mg

Handling, storage & reconstitution

Upstream storage
-20 ± 5 °C

General guidance for this class

Reference standards in the Growth Factors class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

IGF-I Analog sits within the Growth Factors research class (CPC reference ILGF-002). Growth-factor peptides activate receptor tyrosine kinases (EGFR, FGFR, VEGFR, IGF-1R) and downstream RAS–MAPK and PI3K–AKT pathways that drive proliferation, migration, and survival. Investigators typically incorporate IGF-I Analog as a reference standard, tool ligand, or substrate in the assay contexts listed above. Phospho-ERK and phospho-AKT Western blots or AlphaLISA assays are the standard readouts.

Studied for

  • Proliferation and BrdU / EdU assays
  • Wound-healing and scratch-closure models
  • Angiogenesis (tube-formation, aortic ring) studies
  • Regenerative-medicine and stem-cell differentiation work

Frequently asked

What is IGF-I Analog?

IGF-I Analog (CPC catalog code ILGF-002) is a synthetic growth-factor / mitogen peptide in the growth factors category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is IGF-I Analog studied for?

Published and internal research programs use IGF-I Analog as a reference standard in growth factors workflows — for example, proliferation and brdu / edu assays and wound-healing and scratch-closure models. Human clinical evidence is not established.

Is IGF-I Analog FDA-approved for human use?

No. IGF-I Analog is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is IGF-I Analog typically used in the lab?

In a growth factors workflow, IGF-I Analog is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Phospho-ERK and phospho-AKT Western blots or AlphaLISA assays are the standard readouts.

Sources

View full product page →Back to catalog

Related peptides in Growth Factors

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

IGF-II (33-40)
Insulin B (22-25)
H-Asn-Pro-Glu-Tyr(PO3H2)-OH
KGF Receptor Peptide
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.