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Peptides shop · N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat · Reference sheet

N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat

Reference sheet · Endocrine · CPC catalog code GRFF-007

Identity

Name
N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat
Catalog code
GRFF-007
Category
Endocrine

Physicochemical properties

Sequence
Ac-Cys-His-Ser-Gly-Tyr-Val-Gly-Val-Arg-Cys-OMe (trifluoroacetate salt) (Cys1 and 10 bridge)
One-letter
CHSGYVGVRC
Residues
10 amino acids
Modifications
Ac, OMe
Net charge (pH 7)
+1.1 (2 basic / 0 acidic)
Hydrophobic residues
50%
Cysteine present
Yes — disulfide formation and oxidation possible

This sequence carries terminal or reporter modifications (Ac, OMe), so no molecular formula or weight is published here — the modified mass must come from the lot certificate of analysis. Residue composition and charge describe the peptide backbone only. Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.

Reconstitution reference

Volumes for a 1 mg vial of N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.

10 mg/mL
0.1 mL diluent per 1 mg
5 mg/mL
0.2 mL diluent per 1 mg
2 mg/mL
0.5 mL diluent per 1 mg
1 mg/mL
1 mL diluent per 1 mg

Handling, storage & reconstitution

Upstream storage
-20 ± 5 °C

General guidance for this class

Reference standards in the Endocrine class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat sits within the Endocrine research class (CPC reference GRFF-007). Endocrine peptides bind class A/B GPCRs and RTKs on hormone-responsive tissues, triggering canonical cAMP, IP₃/Ca²⁺, and MAPK pathways that regulate secretion, growth, and metabolism. Investigators typically incorporate N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat as a reference standard, tool ligand, or substrate in the assay contexts listed above. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Studied for

  • Receptor-binding and functional selectivity studies
  • Second-messenger (cAMP / IP₁) profiling
  • Hypothalamic–pituitary axis feedback modeling
  • Metabolic and glucose-homeostasis research

Frequently asked

What is N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat?

N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat (CPC catalog code GRFF-007) is a synthetic endocrine research peptide in the endocrine category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat studied for?

Published and internal research programs use N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat as a reference standard in endocrine workflows — for example, receptor-binding and functional selectivity studies and second-messenger (camp / ip₁) profiling. Human clinical evidence is not established.

Is N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat FDA-approved for human use?

No. N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat typically used in the lab?

In a endocrine workflow, N-Acetyl, alpha-TGF (34-43), Methyl Ester, rat is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. HTRF cAMP, calcium mobilization (FLIPR), and radioligand binding are the standard readouts.

Sources

View full product page →Back to catalog

Related peptides in Endocrine

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

alpha-TGF (34-43), rat
[Cys(Acm)20,31] Epidermal Growth Factor (20-31)
Epidermal Growth Factor Receptor Peptide (985-996)
Brain Derived Basic Fibroblast Growth Factor (1-24)
Brain Derived Acidic Fibroblast Growth Factor (1-11)
Brain Derived Acidic Fibroblast Growth Factor (102-111)
SPARC (119-122) (mouse)
N-Acetyl, [Nle4,DPhe7] alpha-MSH (4-10), amide
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.