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Reference sheet · Oncology · CPC catalog code CANC-008
This sequence carries terminal or reporter modifications (Ac), so no molecular formula or weight is published here — the modified mass must come from the lot certificate of analysis. Residue composition and charge describe the peptide backbone only. Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.
Volumes for a 1 mg vial of [Lys(Ac)382]-p53 (374-389); p53 acetylated K382 at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.
Reference standards in the Oncology class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.
[Lys(Ac)382]-p53 (374-389); p53 acetylated K382 sits within the Oncology research class (CPC reference CANC-008). Oncology peptides serve as tumor-targeting ligands (RGD, bombesin, somatostatin analogues), pro-apoptotic mimetics (BH3), or antigenic epitopes for T-cell recognition. Effects are read out in cell viability, receptor binding, and tumor-model contexts. Investigators typically incorporate [Lys(Ac)382]-p53 (374-389); p53 acetylated K382 as a reference standard, tool ligand, or substrate in the assay contexts listed above. MTT / CellTiter-Glo viability, caspase-3/7 activation, and receptor-binding SPR.
[Lys(Ac)382]-p53 (374-389); p53 acetylated K382 (CPC catalog code CANC-008) is a synthetic oncology research peptide in the oncology category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
Published and internal research programs use [Lys(Ac)382]-p53 (374-389); p53 acetylated K382 as a reference standard in oncology workflows — for example, receptor-targeted drug-delivery research and apoptosis and cell-viability assays. Human clinical evidence is not established.
No. [Lys(Ac)382]-p53 (374-389); p53 acetylated K382 is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
In a oncology workflow, [Lys(Ac)382]-p53 (374-389); p53 acetylated K382 is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. MTT / CellTiter-Glo viability, caspase-3/7 activation, and receptor-binding SPR.
Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.