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Peptides shop · Atriopeptin II (rat) · Reference sheet

Atriopeptin II (rat)

Reference sheet · Cardiovascular · CPC catalog code ATPE-002

Identity

Name
Atriopeptin II (rat)
Catalog code
ATPE-002
Category
Cardiovascular

Physicochemical properties

Sequence
H-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-OH (trifluoroacetate salt) (Cys Bridge)
One-letter
SSCFGGRIDRIGAQSGLGCNSFR
Residues
23 amino acids
Molecular formula
C98H158N34O32S2 computed from sequence
Molecular weight
2388.67 g/mol average mass, free peptide, computed
Net charge (pH 7)
+2 (3 basic / 1 acidic)
Hydrophobic residues
35%
Cysteine present
Yes — disulfide formation and oxidation possible

Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.

Reconstitution reference

Volumes for a 1 mg vial of Atriopeptin II (rat) at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.

10 mg/mL
0.1 mL diluent per 1 mg
5 mg/mL
0.2 mL diluent per 1 mg
2 mg/mL
0.5 mL diluent per 1 mg
1 mg/mL
1 mL diluent per 1 mg

Handling, storage & reconstitution

Upstream storage
-20 ± 5 °C

General guidance for this class

Reference standards in the Cardiovascular class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

Atriopeptin II (rat) sits within the Cardiovascular research class (CPC reference ATPE-002). Cardiovascular peptides act on GPCRs and receptor systems in vascular smooth muscle, endothelium, and cardiac myocytes — modulating vasoconstriction, natriuresis, RAAS signaling, or ionotropic responses. Effects are typically measured in isolated vessel, Langendorff heart, or receptor-transfected cell assays.</ Investigators typically incorporate Atriopeptin II (rat) as a reference standard, tool ligand, or substrate in the assay contexts listed above. Radioligand-binding, IP-1 / cAMP HTRF, and organ-bath tension recordings are the standard readouts.

Studied for

  • Vascular reactivity in aortic ring and mesenteric bed preparations
  • Renin–angiotensin–aldosterone system (RAAS) mechanistic studies
  • Natriuretic and diuretic pathway characterization
  • Cardiac remodeling and hypertrophy models

Frequently asked

What is Atriopeptin II (rat)?

Atriopeptin II (rat) (CPC catalog code ATPE-002) is a synthetic cardiovascular research peptide in the cardiovascular category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Atriopeptin II (rat) studied for?

Published and internal research programs use Atriopeptin II (rat) as a reference standard in cardiovascular workflows — for example, vascular reactivity in aortic ring and mesenteric bed preparations and renin–angiotensin–aldosterone system (raas) mechanistic studies. Human clinical evidence is not established.

Is Atriopeptin II (rat) FDA-approved for human use?

No. Atriopeptin II (rat) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Atriopeptin II (rat) typically used in the lab?

In a cardiovascular workflow, Atriopeptin II (rat) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Radioligand-binding, IP-1 / cAMP HTRF, and organ-bath tension recordings are the standard readouts.

Sources

View full product page →Back to catalog

Related peptides in Cardiovascular

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Atriopeptin I (rat)
Atriopeptin III (rat)
Urotensin II , human
Angiotensin II, human
Urocortin II, mouse
Urotensin II , goby
Angiotensin I/II (1-7)
Orn8, Urotensin II, human
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.