What is premature menopause?

Premature menopause occurs when a woman's ovaries stop functioning before the age of 40. This means she will no longer have menstrual periods and her body will produce significantly less estrogen.

What causes premature menopause?

In many cases, the cause of premature menopause is unknown. However, it can be caused by genetic factors, autoimmune diseases, chemotherapy, radiation therapy, or surgical removal of the ovaries.

What are the symptoms of premature menopause?

The symptoms of premature menopause are similar to those of natural menopause and can include hot flashes, night sweats, vaginal dryness, mood changes, and difficulty sleeping. Women may also experience irregular or absent periods before complete cessation.

Does premature menopause affect fertility?

Yes, premature menopause significantly impacts fertility. As the ovaries are no longer releasing eggs, natural conception becomes very unlikely. Women experiencing premature menopause may need to explore alternative family-building options.

What are the long-term health risks associated with premature menopause?

Premature menopause can increase the risk of certain long-term health issues due to lower estrogen levels. These include a higher risk of heart disease, osteoporosis, and cognitive changes if not adequately managed.

Knowledge Graph · Condition

Premature Menopause

Menopause occurring before age 40, also called primary ovarian insufficiency.

Authoritative sources

Evidence base

Systematic Review · 2024
Pharmacogenomic studies of fertility outcomes in pediatric cancer survivors - A systematic review
Clinical and translational science · Stenta T, Assis M, Ayers K, Tucker EJ, et al.
Meta-Analysis · 2024
Bone mineral density in patients with primary ovarian insufficiency: A systematic review and Meta-Analysis
European journal of obstetrics, gynecology, and reproductive biology · Jiang M, Gao Y, Hou H, Guo J, et al.
Meta-Analysis · 2024
Efficacy of intra-ovarian injection of autologous platelet-rich plasma in women with poor responders: a systematic review and meta-analysis
Archives of gynecology and obstetrics · Vahabi Dastjerdi M, Sheibani S, Taheri M, Hezarcheshmeh FK, et al.
Meta-Analysis · 2023
The global prevalence of premature ovarian insufficiency: a systematic review and meta-analysis
Climacteric : the journal of the International Menopause Society · Li M, Zhu Y, Wei J, Chen L, et al.
Meta-Analysis · 2023
Early menopause is associated with increased risk of heart failure and atrial fibrillation: A systematic review and meta-analysis
Maturitas · Liu J, Jin X, Chen W, Wang L, et al.
Randomized Controlled Trial · 2021
Cyclophosphamide-Free Adjuvant Chemotherapy for Ovarian Protection in Young Women With Breast Cancer: A Randomized Phase 3 Trial
Journal of the National Cancer Institute · Yu KD, Ge JY, Liu XY, Mo M, et al.
Meta-Analysis · 2021
Possible modification of BRSK1 on the risk of alkylating chemotherapy-related reduced ovarian function
Human reproduction (Oxford, England) · van der Kooi ALF, van Dijk M, Broer L, van den Berg MH, et al.
Randomized Controlled Trial · 2021
Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice
Human reproduction update · Genazzani AR, Monteleone P, Giannini A, Simoncini T
Meta-Analysis · 2021
Meta-analysis: Early Age at Natural Menopause and Risk for All-Cause and Cardiovascular Mortality
BioMed research international · Huan L, Deng X, He M, Chen S, et al.
Systematic Review · 2021
Hormone replacement therapy and cervical cancer: a systematic review of the literature
Climacteric : the journal of the International Menopause Society · Vargiu V, Amar ID, Rosati A, Dinoi G, et al.

Where Premature Menopause appears on Kindr Health

Data hub

Menopause Statistics

Guide

Amh Test Explained

Wiki

Journal

This page is part of Kindr Health's public Knowledge Graph. Content is for educational purposes only and is not medical advice.