Metformin

Authoritative sources

• Wikidata (Q422129)
• MeSH (D008687)
• Wikipedia

Evidence base

• Randomized Controlled Trial · 2025

  Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial

  JAMA · Pan F, Wang Y, Lim YZ, Urquhart DM, et al.

• Randomized Controlled Trial · 2025

  Efficacy and safety of tirzepatide in children and adolescents with type 2 diabetes (SURPASS-PEDS): a randomised, double-blind, placebo-controlled, phase 3 trial

  Lancet (London, England) · Hannon TS, Chao LC, Barrientos-Pérez M, Pamidipati KC, et al.

• Meta-Analysis · 2024

  Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines

  The Journal of clinical endocrinology and metabolism · Fitz V, Graca S, Mahalingaiah S, Liu J, et al.

• Meta-Analysis · 2024

  Metformin and Combined Oral Contraceptive Pills in the Management of Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis

  The Journal of clinical endocrinology and metabolism · Melin J, Forslund M, Alesi S, Piltonen T, et al.

• Systematic Review · 2024

  Ranking the dietary interventions by their effectiveness in the management of polycystic ovary syndrome: a systematic review and network meta-analysis

  Reproductive health · Juhász AE, Stubnya MP, Teutsch B, Gede N, et al.

• Meta-Analysis · 2023

  Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

  Reproductive biology and endocrinology : RB&E · Greff D, Juhász AE, Váncsa S, Váradi A, et al.

• Randomized Controlled Trial · 2022

  Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial

  JAMA · Dahl D, Onishi Y, Norwood P, Huh R, et al.

• Meta-Analysis · 2022

  Metformin: Is it a drug for all reasons and diseases?

  Metabolism: clinical and experimental · Triggle CR, Mohammed I, Bshesh K, Marei I, et al.

• Meta-Analysis · 2022

  Gastrointestinal adverse events of metformin treatment in patients with type 2 diabetes mellitus: A systematic review, meta-analysis and meta-regression of randomized controlled trials

  Frontiers in endocrinology · Nabrdalik K, Skonieczna-Żydecka K, Irlik K, Hendel M, et al.

• Systematic Review · 2021

  Efficacy and Safety of Metformin for Obesity: A Systematic Review

  Pediatrics · Masarwa R, Brunetti VC, Aloe S, Henderson M, et al.

Where Metformin appears on Kindr Health