Cognitive Decline

Authoritative sources

• Wikidata (Q1436668)
• MeSH (D060825)
• Wikipedia

Evidence base

• Observational Cohort Study · 2023 · Landmark

  Menopausal Hormone Therapy and Risk of Dementia

  BMJ · Pourhadi N, Mørch LS, Holm EA, et al.

  A large Danish study suggested a small association between long-term HRT and dementia risk, but experts caution the study cannot prove HRT causes dementia and contradicts other evidence.

• Randomized Controlled Trial · 2015 · Landmark

  Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women

  PLoS Medicine · Gleason CE, Dowling NM, Wharton W, et al. (KEEPS Cognitive and Affective Study)

  When hormone therapy is started early in menopause, it does not appear to harm memory or thinking, and may improve mood.

• Meta-Analysis · 2025

  A meta-analysis of technology use and cognitive aging

  Nature human behaviour · Benge JF, Scullin MK

• Meta-Analysis · 2025

  The role of the Mediterranean diet in reducing the risk of cognitive impairement, dementia, and Alzheimer's disease: a meta-analysis

  GeroScience · Fekete M, Varga P, Ungvari Z, Fekete JT, et al.

• Meta-Analysis · 2024

  Physical Activity and Cognitive Decline Among Older Adults: A Systematic Review and Meta-Analysis

  JAMA network open · Iso-Markku P, Aaltonen S, Kujala UM, Halme HL, et al.

• Systematic Review · 2024

  Comparative efficacy, tolerability and acceptability of donanemab, lecanemab, aducanumab and lithium on cognitive function in mild cognitive impairment and Alzheimer's disease: A systematic review and network meta-analysis

  Ageing research reviews · Terao I, Kodama W

• Meta-Analysis · 2023

  Cognitive stimulation and cognitive results in older adults: A systematic review and meta-analysis

  Archives of gerontology and geriatrics · Gómez-Soria I, Iguacel I, Aguilar-Latorre A, Peralta-Marrupe P, et al.

• Meta-Analysis · 2023

  The Relationship of Omega-3 Fatty Acids with Dementia and Cognitive Decline: Evidence from Prospective Cohort Studies of Supplementation, Dietary Intake, and Blood Markers

  The American journal of clinical nutrition · Wei BZ, Li L, Dong CW, Tan CC, et al.

• Systematic Review · 2022

  Comparative efficacy of various exercise interventions on cognitive function in patients with mild cognitive impairment or dementia: A systematic review and network meta-analysis

  Journal of sport and health science · Huang X, Zhao X, Li B, Cai Y, et al.

• Meta-Analysis · 2022

  Statin use and risk of dementia or Alzheimer's disease: a systematic review and meta-analysis of observational studies

  European journal of preventive cardiology · Olmastroni E, Molari G, De Beni N, Colpani O, et al.

• Meta-Analysis · 2022

  Effects of reminiscence therapy in people with dementia: A systematic review and meta-analysis

  Journal of psychiatric and mental health nursing · Saragih ID, Tonapa SI, Yao CT, Saragih IS, et al.

• Meta-Analysis · 2022

  B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis

  Nutrition reviews · Wang Z, Zhu W, Xing Y, Jia J, et al.

Where Cognitive Decline appears on Kindr Health