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Non-Hormonal · Evidence-Based · Clinician-Led

Stop Taking Daily Antidepressants for Your Period.

PMDD is cyclical. Your treatment should be too. The Kindr Cycle-Sync Protocol uses evidence-based luteal-phase SSRI targeting paired with a non-hormonal supplement pack and digital tracking to help reduce PMDD symptoms — without the daily side effects of continuous dosing.

Kindr Health · NPI 1609792902 Cancel anytime
Kindr
Cycle-Sync
Precision Kit
14-Day Luteal Support
Myo-Inositol · Magnesium Glycinate
KINDR · TODAY
Day 19
Luteal phase active
Take your Precision Protocol pack now.
The Clinical Insight

The Problem with Standard PMDD Treatment

Most doctors prescribe daily SSRIs for PMDD. You don't need serotonin every day — you only need it during your luteal phase (the 14 days before your period). Daily dosing causes weight gain, libido loss, and emotional numbness. Kindr Health clinicians specialize in Luteal-Phase Dosing: the clinically proven strategy of targeting PMDD only when it happens.

Your 28-Day Cycle
Days 1–14 · No medication neededDays 15–28 · Kindr Protocol active
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What's Inside

A complete cycle, in one box.

Medical
The Telehealth Script
A 15-min online consult with a Kindr clinician to prescribe an FDA-approved SSRI, strictly calibrated for luteal-phase-only use.
14-Day Luteal Support Packs
Physical
14-Day Luteal Support Packs
Pharmaceutical-grade Myo-Inositol 2,000mg, Magnesium Glycinate 300mg, B6 (P-5-P) 50mg, and L-Theanine 200mg. One stick pack daily during your luteal window — bypasses pill fatigue, supports serotonin & GABA.
Buy the packs standalone · $49
Digital
The Cycle-Sync App
Daily SMS reminders telling you exactly when to start, dose, and stop your protocol based on your unique cycle length.
60-Second Check

Is it PMDD, or just PMS?

Tap every symptom you experience in the 1–2 weeks before your period.

Your Protocol

Start the Cycle-Sync Kit

Total today$149/mo
No hormones. HIPAA-compliant. Kindr clinicians · NPI 1609792902.
Medically Reviewed
Dr. Elena Vasquez, MD — Reproductive Psychiatry
Board-certified. Kindr Health, Inc. · NPI 1609792902 · Last clinical review: July 1, 2026.
Head to Head

Cycle-Sync vs. Daily SSRI vs. Doing Nothing

Kindr Cycle-SyncDaily SSRIDo Nothing
Dosing scheduleLuteal-only (14 days)Every day, forever—
Weight gain riskLowModerate–High—
Libido impactNeutralCommon decrease—
Emotional bluntingRareCommon—
Cycle-synced remindersIncludedNoNo
Non-hormonalYesYesYes
Physician oversightIncludedVariesNo
Monthly cost$149$25–$200+ w/ visits$0 (symptom cost is high)
Dosing schedule
Kindr Cycle-SyncLuteal-only (14 days)
Daily SSRIEvery day, forever
Do Nothing—
Weight gain risk
Kindr Cycle-SyncLow
Daily SSRIModerate–High
Do Nothing—
Libido impact
Kindr Cycle-SyncNeutral
Daily SSRICommon decrease
Do Nothing—
Emotional blunting
Kindr Cycle-SyncRare
Daily SSRICommon
Do Nothing—
Cycle-synced reminders
Kindr Cycle-SyncIncluded
Daily SSRINo
Do NothingNo
Non-hormonal
Kindr Cycle-SyncYes
Daily SSRIYes
Do NothingYes
Physician oversight
Kindr Cycle-SyncIncluded
Daily SSRIVaries
Do NothingNo
Monthly cost
Kindr Cycle-Sync$149
Daily SSRI$25–$200+ w/ visits
Do Nothing$0 (symptom cost is high)
Who this is for
  • Women with cyclical rage, hopelessness, or crying spells 1–2 weeks before their period.
  • Anyone who tried daily SSRIs and quit because of side effects.
  • Members of the Kindr ecosystem who want a physician-led PMDD plan.
  • Women whose OB/GYN dismissed symptoms as "just PMS".
Who this isn't for
  • Women who are pregnant, breastfeeding, or actively trying to conceive.
  • Anyone currently taking MAOIs or a daily SSRI without prescriber coordination.
  • Post-menopausal women (no luteal phase to sync to — see our HRT protocol).
  • Anyone in an active mental-health crisis — call or text 988.
Frequently Asked

Answers, physician-reviewed.

What is PMDD, and how is it different from PMS?
PMDD (Premenstrual Dysphoric Disorder) is a DSM-5 diagnosis affecting 5–8% of menstruating women. It causes severe, cyclical mood symptoms — rage, hopelessness, brain fog, and sometimes suicidal ideation — that reliably resolve within days of menstruation. PMS is milder and usually does not impair daily functioning.
What is luteal-phase SSRI dosing?
Luteal-phase (or intermittent) SSRI dosing means taking an SSRI only during the 14 days before your period, rather than every day. Multiple randomized trials — including work by Halbreich, Freeman, and Steiner — show it is as effective as daily dosing for PMDD with fewer side effects (weight gain, libido loss, emotional blunting).
Is this hormonal treatment?
No. The Cycle-Sync Protocol is fully non-hormonal. Luteal Support Packs are supplement-based (Myo-Inositol, Magnesium, B6, L-Theanine). If your clinician determines an SSRI is appropriate, it is a serotonergic — not hormonal — medication.
Do I need a diagnosis before starting?
No formal diagnosis is required to begin the supplement protocol. If you and a Kindr clinician determine an SSRI is appropriate, the telehealth visit includes a validated PMDD screening (DRSP or PSST) as part of your assessment.
What if I already take a daily SSRI?
Do not stop your medication. Book a consult and our clinicians will coordinate with your prescriber on whether a luteal-only transition is appropriate for you.
Is Kindr Health covered by insurance?
Kindr operates on a transparent cash-pay model. Many members submit our itemized superbill for HSA/FSA reimbursement. Prescription SSRIs are typically inexpensive with or without insurance coverage.
How fast will I see results?
Most members report meaningful symptom reduction within 2 complete cycles. Full stabilization typically takes 2–3 cycles as the protocol calibrates to your unique luteal window.
Can I cancel my subscription?
Yes — cancel anytime from your Kindr account, no questions asked. Your Luteal Support Packs continue to ship on your cycle unless paused.
Clinical References
  1. Halbreich U, et al. Efficacy of intermittent, luteal-phase sertraline treatment of premenstrual dysphoric disorder. Obstet Gynecol. 2002. PubMed 12468170
  2. Freeman EW, et al. Continuous or intermittent dosing with sertraline for PMDD. Am J Psychiatry. 2004. PubMed 14992971
  3. Nemets B, et al. Myo-inositol treatment of premenstrual dysphoric disorder. J Clin Psychopharmacol. 2002. PubMed 12042196
  4. Boyle NB, et al. The effects of magnesium supplementation on subjective anxiety and stress — a systematic review. Nutrients. 2017. PubMed 28445426
  5. Wyatt KM, et al. Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review. BMJ. 1999. PubMed 10334745
Reviewed by Dr. Elena Vasquez, MD (NPI 1609792902) · Kindr Health medical review process.
Kindr Luteal Support Packs
Supplement · No Rx
Just want the Luteal Support Packs?
Non-hormonal Myo-Inositol + Magnesium + B6 + L-Theanine stick packs — perfect as a first step or as a companion to your existing PMDD plan.
Shop Luteal Packs · $49
Kindr Health, Inc. · NPI 1609792902
The Cycle-Sync Precision Kit provides evidence-informed education, supplementation, and a pathway to a licensed clinician for luteal-phase SSRI prescription where appropriate. Not a substitute for individualized medical advice. If you experience suicidal thoughts, contact 988 or seek emergency care immediately.

Physician-supervised honesty

Who this protocol is not for

  • You are currently having suicidal thoughts or are in crisis — call or text 988 (Suicide & Crisis Lifeline) now. This protocol is not an emergency service.
  • You have bipolar disorder that has not been evaluated by a psychiatrist. SSRIs can trigger mania without proper stabilization.
  • You are already on a daily SSRI that is working well — do not stop your medication; book a consult so a clinician can coordinate with your prescriber.
  • You are pregnant or breastfeeding, or planning pregnancy in the next 3 months.
  • You want continuous, non-cyclical treatment. This protocol is specifically for luteal-phase dosing.

If any of the above applies, this protocol is likely not the right first step. Talk to a clinician about a better fit.

Where this fits in the kindr ecosystem

Every kindr protocol is designed to coordinate with the others. Skin, cycle, and metabolism are the same physiology — treated as separate silos, none of them fully work.

How care is coordinated

Where you are in the cycle

Related symptoms

See the products

Reviewed by the kindr Health medical team · Last reviewed July 14, 2026